N-[(5-Fluoro-2,3-dihydro-4-benzofuranyl)methyl]-8-(2-methyl-3-pyridinyl)-1,2,4-triazolo[4,3-c]pyrimidin-5-amine
MAK-683
CAS: 1951408-58-4
Molecular Formula: C20H17FN6O
N-[(5-Fluoro-2,3-dihydro-4-benzofuranyl)methyl]-8-(2-methyl-3-pyridinyl)-1,2,4-triazolo[4,3-c]pyrimidin-5-amine - Names and Identifiers
N-[(5-Fluoro-2,3-dihydro-4-benzofuranyl)methyl]-8-(2-methyl-3-pyridinyl)-1,2,4-triazolo[4,3-c]pyrimidin-5-amine - Physico-chemical Properties
| Molecular Formula | C20H17FN6O |
| Molar Mass | 376.39 |
| Density | 1.47±0.1 g/cm3(Predicted) |
| pKa | 2.70±0.12(Predicted) |
| Storage Condition | Room Temprature |
N-[(5-Fluoro-2,3-dihydro-4-benzofuranyl)methyl]-8-(2-methyl-3-pyridinyl)-1,2,4-triazolo[4,3-c]pyrimidin-5-amine - Reference Information
| biological activity | MAK683 (EED inhibitor-1, example 2) is an inhibitor of embryonic ectoderm development (EED). The corresponding IC50 values of MAK683 in EED Alphascreen binding, LC-MS and ELISA analysis are 59 nM, 89 nM and 26 nM respectively. |
| target | TargetValue EED (ELISA say) 26 nM EED (EED Alphascreen binding say) 59 nM EED (LC-MS say) 89 nM |
| Target | Value |
| EED (ELISA assay) | 26 nM |
| EED (EED Alphascreen binding assay) | 59 nM |
| EED (LC-MS assay) | 89 nM |
Last Update：2024-04-09 19:05:05
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Product Name: MAK683 Visit Supplier Webpage Request for quotationCAS: 1951408-58-4
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Product Name: MAK683 Visit Supplier Webpage Request for quotationCAS: 1951408-58-4
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Product Name: MAK683 Visit Supplier Webpage Request for quotationCAS: 1951408-58-4
Tel: +86-400-900-4166
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Mobile: +86-18621343501
QQ: 2881950922
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Product Name: EED inhibitor-1 Visit Supplier Webpage Request for quotationCAS: 1951408-58-4
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Product Name: MAK-683 Visit Supplier Webpage Request for quotation
CAS: 1951408-58-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
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CAS: 1951408-58-4
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View History
N-[(5-Fluoro-2,3-dihydro-4-benzofuranyl)methyl]-8-(2-methyl-3-pyridinyl)-1,2,4-triazolo[4,3-c]pyrimidin-5-amine
328014-49-9
165383-59-5
5-(3-allyl-5-ethoxy-4-hydroxybenzylidene)-3-cyclohexyl-2-[(4-ethylphenyl)imino]-1,3-thiazolidin-4-one
4-(2,4-Dihydroxyphenylazo)-5-hydroxy-2,7-naphthalenedisulfonic acid disodium salt
N-[4-(aminosulfonyl)phenyl]-2-[(4,5-diphenyl-1,3-oxazol-2-yl)thio]acetamide
475586-45-9
RVX-208(RVX 000222)
723324-89-8
73927-28-3
328014-49-9
165383-59-5
5-(3-allyl-5-ethoxy-4-hydroxybenzylidene)-3-cyclohexyl-2-[(4-ethylphenyl)imino]-1,3-thiazolidin-4-one
4-(2,4-Dihydroxyphenylazo)-5-hydroxy-2,7-naphthalenedisulfonic acid disodium salt
N-[4-(aminosulfonyl)phenyl]-2-[(4,5-diphenyl-1,3-oxazol-2-yl)thio]acetamide
475586-45-9
RVX-208(RVX 000222)
723324-89-8
73927-28-3